The skin dries and cracks, letting in more microbes. I am a hand- washer from before this. Every time I would come back in the office, my first stop was the bathroom to wash my hands, even if I had to go or not. I would also wash my hands BEFORE I would take a wizz, because I knew where my Johnson was from the time I showered in the morning, until I walked into the bathroom. But didn't know who touched the counter top or door handles before I touched them.
But with this increased need to wash hands, they are getting very dry and cracked. That poses a hazard with an increased avenue for microbes to get into the cracks and openings. Gloves are a good idea.